ea0059p006 | Adrenal and steroids | SFEBES2018
Stoye David
, Gyllenhammer Lauren
, Andrew Ruth
, Boardman James
, Entringer Sonja
, Buss Claudia
, Wadhwa Pathik
, Reynolds Rebecca
Background: Both excess and insufficient glucocorticoid exposure in utero is associated with adverse fetal outcomes. Characterising the maternal hypothalamic-pituitary-adrenal (HPA) axis is challenging with large intra-individual variations in plasma and saliva. We hypothesised that 24-hour total urinary glucocorticoid (TUG) is a marker of maternal HPA axis during pregnancy. We tested associations of TUG with maternal BMI and birthweight.Methods: TUG was...